“十二五”国家重点图书：细胞力学进展（英文版）

Advances in Cell Mechanics is a groundbreaking academic research book that compiles nine original research works on molecular and cellular biomechanics. The book provides a comprehensive overview of the current state of cell mechanics research and offers unique insights into emerging research directions. Chapter 1 presents a detailed analysis of modeling and simulations of growing cell clusters, discussing single cell geometry, material models, cell interactions, and the cell life cycle, among other things. Chapter 2 provides a multiscale biomechanical modelling of stem cell-extracellular matrix interactions, with a discussion of the meshfree Galerkin formulation and contact and adhesion models. Chapter 3 focuses on the modeling of proteins and their interactions with solvents, highlighting various molecular dynamics simulations, such as quasi-harmonic analysis and equilibrium conformational analysis.Chapter 4 delves into the structural, mechanical, and functional properties of intermediate filaments in cells, while Chapter 5 discusses cytoskeletal mechanics and rheology, including the relationship between cytoskeletal mechanics and cancer biology. Chapter 6 examines the application of multiphasic theories to the problem of tissue engineering, discussing the use of computational models for tissue growth and regeneration. Chapter 7 explores the effect of substrate rigidity on the growth of nascent adhesion, highlighting the use of traction force microscopy. Chapter 8 presents an innovative opto-hydrodynamic trapping technique for single-cell biomechanics, while Chapter 9 discusses the application of nonlocal shell models to microtubule buckling in living cells. The book culminates in four appendices and an extensive list of references.Advances in Cell Mechanics is an essential resource for professionals and students alike who are interested in the rapidly evolving field of cell mechanics research. The book offers a unique perspective on the current state of cell mechanics research as well as emerging research directions. The comprehensive and accessible nature of the book makes it an ideal textbook for courses in biomechanics, tissue engineering, and cellular biology. I highly recommend this book to any reader interested in a deeper understanding of the mechanics of cells and tissues.